1. Give a brief description of each of the following:
a.heritable mutation
b.nutritional mutation
c.conditional mutation
2. a.Write a wild-type DNA sequence with 10 bases and under it write the sequence after a transversion and a transition has occurred. Underline and label both mutations.
b.Write a DNA sequence of 10 bases, and show how a missense mutation results in a mutant sequence. Show the sequence of the transcript and hypothetical amino acid sequence.
c.Repeat part b., but this time show the consequences of a frameshift mutation?
3. a.Give an example of a spontaneous mutation.
b.Describe what type of mutation results from exposure to UV light.
c.When DNA in a cell undergoes a UV radiation-induced mutation, what are the two possible options for this cell?
4. Describe an experiment you would do to determine if a food preservative was a mutagen.
5. a.In a suburb of New York, out of 135,000 people, 64 had a dominant genetic disease; 4 of these individuals had an affected parent. What is the mutation rate for this gene?
b.What does this value mean?