Assignment task:
70 year old patient. The patient was prescribed Apraclonidine by an ophthalmologist. He been treated with Verapamil and Salbutamol for years. The patient visited the ophthalmologist at 3 months to review his eye medication. After, Apraclonidine eye drops were ceased and Timolol eye drops were initiated. Her updated medications consist of
Timolol 0.5 % eye drops 1 drop twice daily both eyes
Not long after administration of Timolol Eye Drops he had a fall. He reported had been feeling 'dizzy' when going from lying down, or sitting down to standing up.
QUESTIONS:
Q1. Why was Timolol used instead of Apralonidine for this patient?
Q2. How did the therapeutic consequences of multi drug use (timolol and verapamil (calcium channel blcoker) lead to the patient feeling dizzy and fall?
Q3. What are the mechanisms for drug action required?