Why igg and iga antibodies are generally of higher afinity, Other Subject

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Why igg and iga antibodies are generally of higher afinity

Problem

1) With reference to the concept of 'afinity maturation', briefly explain why IgG and IgA antibodies are generally of higher afinity than IgM antibodies.

2) Despite this, IgM antibodies can be very effective in activating complement and promoting phagocytosis of bacteria. Provide an explanation for this observation.

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Other Subject: Why igg and iga antibodies are generally of higher afinity

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