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While preparing for a clinical trial to test a new drug to

While preparing for a clinical trial to test a new drug to control hypertension, a pilot study with 10 volunteers was conducted to determine how much SBP can change over time if it goes untreated. After 4 weeks, you discover a mean = 0.9 with a 95% CI -4.1 to 2.3. A reviewer stated that these results do not mean anything because blood pressure cannot be a negative value. Do you agree or disagree with this reviewer and explain why or why not?

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