Which of the following is a major disadvantage to the use of chemical mutagens, aside from the obvious fact that they are dangerous to handle?
A) Most of the mutations induced are immediately lethal.
B) Most chemically induced changes are detectable only by sequencing.
C) Chemical mutagens activate transposons.
D) Two or more generations of further matings are required to isolate them.
E) Chemical mutagens alter all A-T and C-G base pairing.