Question: You want to address whether a NMDAR subunit is required for synaptic plasticity, so you want to drive expression in all neurons using the synaptotagmin promoter in mice. In your own words, briefly describe the Cre-Lox system and its application in creating this cell-specific knockout in mice. In your response, include the roles of 1) Cre recombinase, 2) LoxP sites, and 3) the placement of your gene of interest (NMDAR-2D) to create this knockout strain (2 pts each). Need Assignment Help?