Where can the o antigen affect in shigella


Problem:

The O antigen is synthesised by Pathology islands (PAI). O antigen may be a factor why Shigella survives the passage through host defences. I am interested in which step of pathogenesis.

There are Bacterial ATPase (actin tail, intracellular movement), M-cell (enter) ...-> extracellular movement.

Required:

Question: Where can the O antigen affect in Shigella?

Could someone explain this to me?

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