What would be an explanation of this phenomenon, Biology

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What would be an explanation of this phenomenon

Problem

a) Although DNA mutations do occur despite an editing system, the resulting protein is not always changed. What would be an explanation of this phenomenon?

b) Although lactose intolerance is not a lethal mutation, it was at one time in human history. Can you explain this?

c) How are plasmids used in Biotechnology?

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Biology: What would be an explanation of this phenomenon

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Biology: What would be an explanation of this phenomenon

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