Problem
Read the journal article "Familial Dysautonomia: Mechanisms and Models" by Paula Dietrich and Ioannis Dragatsis and write an analysis of the introduction. It is important to back up your analysis with other references, which you will source and cite.
You are required to summarise, in your own words, the following aspects of the article's Introduction:
• The disease that the article is related to. i.e. what is the disease? What is the significance of this disease? Why is it important to study?
• What specific aspect of the disease is being investigated in the study? i.e. what is the mechanism (e.g. signaling pathway) being targeted in this study and why?
• If a particular experimental intervention/treatment is mentioned in the Introduction section (e.g. drug, type of nucleic acid, viral vector, etc..), how does it work and why use that particular approach?
• The Aim(s) and hypothesis of the study in relation to the background material given in the Introduction. What is the rationale for this study?
• If the hypothesis of the study is supported by the results, how significant will this be in terms of understanding or treating the disease?