Problem
We isolate a strain of E. coli with an inactivating mutation in mutT, leading to an accumulation of free 8-oxoG-triphosphate that can be incorporated during replication. Remember that 8-oxoG can base pair with either cytosine, or adenosine, and so can be introduced into the DNA during replication opposite adenosine. If this happens, what mutation will now be caused by the action of the MutY protein?
None. MutY only fixes problems and MutY, MutT are redundant.
AT -> CG transition
AT -> CG transversion
GC -> TA transition
GC -> TA transversion.