What mass of jafrasitor should be administered


The drug jafrasitor (molecular weight 540 daltons) binds the histone deacetylase enzyme Sir2 with a dissociation constant of 0.1nM. What mass of jafrasitor should be administered to a patient with a blood volume of 5.5L such that Sir2 is at least 91% inhibited?

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Biology: What mass of jafrasitor should be administered
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