What is topological analysis


Problem:

I know that it is usually considered a double membrane like those surrounding mitochondria and chloroplasts, but I read a review that stated "according to topological details it is actually a single lipid bilayer; this distinction is important"

Question: Could anyone please explain how this is true and why the distinction is important?

Question: Why this topological analysis wouldn't apply to other membranous structures in the cell?

Please provide proper answers for these questions.

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Biology: What is topological analysis
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