What is the usual recommendation regarding treatment of, Biology

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What is the usual recommendation regarding treatment of

What is the usual recommendation regarding treatment of patients receiving cyclophosphamide who have the side effect of protracted, severe hemorrhagic cystitis?

a. Reduce the dose by half for the subsequent treatments

b. Provide vigorous prehydration to avoid the side effect in the future

c. Discontinue treatment

d. Hold the next cycle of treatment, then resume treatment

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