What is the structure (including functional groups)? Stereochemistry (racemic or single enantiomer)?
• Does the structure conform to the "Lipinski's Rule of Five"?
• What is the function? What is the biological target?
• How does the structure relate to function and target?
• Synthesis of the drug (known, not your own). Highlight the steps, which include reactions from CHEM 320 material.
Also, typical peer and instructor evaluation criteria (subject to minor changes) Guidelines:
• Include references for your sources (including images and structures not created by you)
• 10 slides or less, including title slide etc.
• No external links (10 slides is all you get)
• If the topic contains specific drug names, you must cover all of them
Criteria 1 organization and originality
? Was the information presented in a clear and logical way?
? Did it leave you feeling you have learned something new and relevant?
Criteria 2 organic chemistry relevance
Was there enough chemistry presented to make the assignment as relevant as possible to organic chemistry material (i.e., clear reaction drawings as opposed to wordy descriptions etc.)?
Criteria 3 comparison and analysis
If the topic had more than one drug, did the presenters compare and contrast the drugs in terms of structure/function differences (as opposed to just listing one drug after another etc.)?
Criteria 4 format - esthetical issues
? Was the presentation visually appealing?
? Were there any editorial issues (i.e., typos, hard-to read or overlapping items on a slide)
Criteria 5 format - ethical issues
?Were there no more than 10 slides? Were there no attempts to circumvent the slide limit?
?Were there any objectionable or borderline objectionable statements and images?