What is the root cause of sickle-cell anemia


Discussion:

Molecular Biology - Multiple Choice

1. Which of the following is an accurate statement concerning the differences between DNA and RNA?

  • a. RNA is usually double-stranded, but DNA is usually single-stranded.
  • b. RNA has the sugar deoxyribose, but DNA has the sugar ribose.
  • c. RNA contains three different nucleotides, but DNA contains four different nucleotides.
  • d. RNA lacks the base thymine (which is found in DNA) and has uracil instead.

2. The DNA sequence of a codon in a gene was changed from AAT to AAC. This type of mutation is called a(n) __________.

  • a. point mutation
  • b. insertion mutation
  • c. deletion mutation

3. The cells in your skin have a different shape and different function from the cells in your liver because the two types of cells have different __________.

  • a. DNA
  • b. proteins
  • c. lipids
  • d. carbohydrates

4. Genetic recombination (crossing over) produces __________.

  • a. new chromosomes
  • b. mutations
  • c. new combinations of alleles
  • d. longer chromosomes

5. Which one of the following statements is true?

  • a. An allele is either dominant or recessive, not in between.
  • b. A particular gene can have only two alleles.
  • c. A single trait can be affected by many different genes.
  • d. The environment is irrelevant to gene expression.

6. What is the root cause of sickle-cell anemia?

  • a. mutations in the gene that directs the synthesis of the hemoglobin protein
  • b. an amino acid substitution in the hemoglobin protein
  • c. malaria
  • d. abnormally shaped red blood cells

7. What are restriction enzymes?

  • a. enzymes that are limited (i.e., restricted) in how big they can become
  • b. vitamins such as vitamin A
  • c. plasmids
  • d. enzymes that cleave through a DNA helix wherever they encounter a specific sequence of nucleotides

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