Question 1: In a particular population with a mean inbreeding coefficient of 0.005, a rare recessive disease is caused by an allele with a frequency of 0.005. What is the ratio of diseased homozygotes in this population compared to that in a random mating population? Need Assignment Help?
Question 2: Compute the inbreeding coefficient for an offspring of each of the following:
(a) a self-fertilizing parent
(b) full siblings
(c) first cousins
Question 3: In a population in which the genotype frequencies of DD, Dd, and dd are 0.056, 0.288 and 0.656 respectively. Find p and F.
Question 4: At a particular locus, there are three alleles: A, T and C. The genotypic counts in the sample are AA:109, AT:59, CC:20 and TT:200.
A. Find the expected homozygosity and expected heterozygousy of the population.
B. What is the inbreeding coefficient of this population?
C. Use the inbreeding coefficient you calculated and the allele frequencies to find the observed genotype counts (even though you already have them).