What is the probability that a b blood stain in the us


The forensic use of ABO blood groups and VNTR allele frequencies

Frequencies of ABO and Rh blood types in the United States

 

U.S. Caucasian

U.S. Black

U.S. Asian

0

0.45

0.48

0.40

A

0.40

0.27

0.28

B

0.11

0.21

0.24

AB

0.04

0.04

0.08

Rh+

0.85

0.90

0.99

Rh-

0.15

0.10

0.01

a) What is the probability that a B+ blood stain in the US lefta at the scene of a crime randomly matches a person of the following ancestry

Caucasian
Black
Asian

A genetic sytem that is far more variable than the simple blood types consists of atretches of DNA called VNTRs (variable number of tandem repeats). Each of thes VNTR (also known as minisatellites) loci contain many alleles, most of which are very rate.

Binned

VNTR Locus D1S7

Frequencies in Caucasians        Blacks

Binned a Caucasian D2S44

Ilele frequencies in samples at VNTR loci D17S79  D4S139

Allele

(n=605)

(n=372)

(n=802)

(n=563)

(n=460)

1

0.004

0.007

0.005

0.010

0.004

2

0.006

0.009

0.003

0.003

0.010

3

0.009

0.011

0.016

0.007

0.006

4

0.012

0.007

0.024

0.004

0.014

5

0.011

0.016

0.046

0.015

0.033

6

0.014

0.020

0.034

0.223

0.024

7

0.010

0.011

0.123

0.199

0.040

8

0.029

0.035

0.106

0.263

0.047

9

0.021

0.023

0.084

0.200

0.054

10

0.014

0.030

0.049

0.029

0.071

11

0.028

0.030

0.083

0.032

0.108

12

0.031

0.026

0.039

0.010

0.190

13

0.046

0.044

0.041

0.006

0.129

14

0.067

0.069

0.039

 

0.095

15

0.057

0.065

0.087

 

0.036

16

0.061

0.073

0.089

 

0.036

17

0.069

0.054

0.075

 

0.103

18

0.055

0.051

0.022

 

 

19

0.060

0.047

0.018

 

 

20

0.063

0.063

0.008

 

 

21

0.079

0.062

0.008

 

 

22

0.077

0.060

 

 

 

23

0.077

0.074

 

 

 

24

0.032

0.017

 

 

 

25

0.019

0.027

 

 

 

26

0.050

0.071

 

 

 

b) Calculate the probability that an individual picked at random from the Caucasian population has the following genotype (allele 1/allele 2)

5/22 heterozygote at D1S7
6/8 heterozygote at D2S44
5/9 heterozygote at D17S79
12/12 homozygote at D4S139

c) What is the probability that an individual has full multilocus DNA profile in b)?

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