Problem
I. A bacterium from a bacterial infection in an individual avoided the lysis and opsonisation by the complement proteins. Explain the different scenarios that could have occurred and would have led to this infection?
II. Macrophages play a central role in chronic inflammatory disorders. Justify this statement by explaining the concept of inflammation and by giving examples of where this takes place.
III. William Tucker is a 31-year-old male who developed an infection followed by an increase in the secretion of cytokines and overactivation of T cell response. The diagnostic analysis suggested a bacterial toxin in the body. What is the most probable reason for the cytokine storm, and explain this phenomenon?