What is the mechanism of action of a proton pump inhibitor, Biology

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What is the mechanism of action of a proton pump inhibitor

Question: What is the mechanism of action of a proton pump inhibitor (PPI)? Prevents gastrin from activating the parietal cell? Inhibits mucus production in the intestine? Irreversibly blocks pepsin from release of the parietal cell? Irreversibly blocks the hydrogen-potassium-adenosine triphosphatase (ATP) pump ?

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