What is the hypothesis to be tested with an rct


Problem

Chen S, Underwood BR, Jones PB, Lewis JR, Cardinal RN. 2022. Association between lithium use and the incidence of dementia and its subtypes: a retrospective cohort study. PLOS Medicine. 19(3): e1003941.

Make sure it is that article with that title.

• Was the hypothesis supported?
• Why is a randomized controlled trial (RCT) needed to test whether lithium can prevent dementia?
• What is the hypothesis to be tested with an RCT?

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