Assignment
A 47-year-old female presents with Stage IV breast cancer. Today, the PET scan reveals brain metastasis.
• Define proliferation and differentiation and relate these changes to cancer.
• Describe invasion, angiogenesis and metastasis.
• There are three underlying causes of growth and maturity abnormalities: telamerase, pRB changes and 53 changes. Discuss these in relation to the patient.
• Discuss tumor suppressor genes, oncogenes and DNA repair genes.
A 30-year-old presents with a history of IV drug use, HIV +, and is today diagnosed with pneumonia.
• Does the patient have an acute or chronic state of inflammation? Explain the rationale.
• What is the significance of cellular replication in a patient with HIV?
• What is viral load and what is the relationship with CD4 T cells?
• How did the pneumonia occur?
A 25-year-old male presents with chronic sinusitis and allergic rhinitis.
• Define innate vs. acquired immunity.
• Define active vs. passive immunity.
• Discuss the genetic predisposition of allergens.
• Describe the antigen-antibody response.
• What is the pathology of sinusitis?
A 40-year-old has an endometrial biopsy report: benign endometrial hyperplasia.
• Explain the diagnosis.
• Which cells are implicated in this diagnosis? Compare and contrast atrophy vs. hyperplasia.
• How does dysplasia differ from hyperplasia?
• Does hyperplasia lead to neoplasia? Defend your answer.
Format your assignment according to the give formatting requirements:
• The answer must be using Times New Roman font (size 12), double spaced, typed, with one-inch margins on all sides.
• The response also includes a cover page containing the student's name, the title of the assignment, the course title, and the date. The cover page is not included in the required page length.
• Also include a reference page. The references and Citations should follow APA format. The reference page is not included in the required page length.