Thermal Psychro-, meso-, thermo-, hyperthermophilic bacteria/archaea -10C (Antarctic ice, permafrost in Siberia and Canada) Colwellia spp, Psychrobacter spp +110C (deep sea hydrothermal vents, hot springs) Pyrococcus spp, Methanococcus spp >300 sequenced genomes Simplest eukaryotes: up to ~60C (nematode from hot springs)' Cold-blooded animals: Notothenia spp. Antarctic fish: -1.8C habitat, dies of overheating at +6C = 40F Desert iguana: up to +60C Very few complete genomes! Is habitat temperature reflected in the genomes? What is presumably related to thermostability?