What is meant by the sequential assembly of an experimental, Basic Statistics

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What is meant by the sequential assembly of an experimental

What is meant by the "sequential assembly of an experimental design"? Illustrate the sequential assembly of a three-factor central composite design beginning with a half fraction of a 23 system. Suppose you suspected that shifts in response might occur between the addition of parts of the design. How would this affect your design and analysis?

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Basic Statistics: What is meant by the sequential assembly of an experimental

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