Assignment Problem: CB is a 66 year old male with a history of DVT who has been followed in the clinic for the past 1 year after suffering a DVT post-surgery. He is receiving Coumadin and INR has been carefully maintained between 2-3 for the past year. He is seen monthly in the clinic. His physical exam is unremarkable today in the clinic and he has no complaints. His labs resulted with PT at 55 seconds and INR at 19.4.
1- What is DVT and how common is it?
2- What is Warfarin
3- What is INR and how is it calculated?
4- What is the danger of a greatly prolonged PT and INR?
5- What factors increase the PT
6- What factors enhance the effects of Warfarin?
7- What factors decrease the PT
8- What factors reduce the effects of Warfarin?
9- What should be done for CB next?
10- What are the possible therapeutic options?