Assignment
Shirley, D.A.T., Farr, L., Watanabe, K., Moonah, S., (2018) A Review of the Global Burden, NewDiagnostics, and Current Therapeutics for Amebiasis, Open Forum Infectious Diseases, Jul 5;5(7). doi:10.1093/ofid/ofy161
Answer the following according to the article
I. Approx. how many people die every year, world-wide, from amebic colitis?
II. What is the incidence of amebiasis in travelers returning to the United States?
III. What is the highest recent prevalence estimated (through serological testing) for E. histolytica in various world regions (e.g. rural Mexico)?
IV. About what % of E. histolytica infections are symptomatic?
V. As described in the article, what are the risk factors for developing fulminant forms of amebic colitis?
VI. Which gender is more likely to experience amebic liver abscesses and over what age does it usually occur?
VII. While symptoms of amebiasis can develop in 2-4 weeks after exposure, including liver abscess, what is the longest period of time reported between travel to endemic areas and the development of hepatic amebiasis? (making any travel history relevant to diagnosis).
VIII. What is the 'gold-standard' for diagnosis/detection of Amebiasis (endorsed by the WHO), but what are its limitations?
IX. What are the preventative measures outlined in the article to reduce the incidence of amebiasis?