What is Human Glucose Transporters (GLUT)?
All GLUTS are the integral proteins, which penetrate and span the lipid bilayer of plasma membrane. Six isomers of GLUT have been described, the tissue distribution of which is given below:
GLUT 1 - Erythrocytes, blood, brain barrier, placenta
GLUT 2 - Liver, P cells of pancreas, kidney, and small intestine
GLUT 3 - Brain
GLUT 4 - Adipocytes, heart, skeletal mluscle
GLUT 5 - Small intestine
GLUT 7 - Endoplasmic reticulum of hepatocytes