Assignment:
Question 1. What is the purpose of a Phase 2 trial?
o to assess safety (of a new drug)
o to test efficacy (does a new drug work?)
o to compare to new drug to a standard treatment
Question 2. What is a placebo?
o another name for the investigational treatment received by the experimental group
o the combination of standard and investigational treatments received by the experimental group
o a "fake" treatment
o another name for the standard treatment received by the control group
Question 3. What is double-blinding?
o when neither the participants nor the researchers know which treatment is being administered
o when the participants don't know which treatment they are receiving
o when the placebo is administered to the experimental group
o when both the participants and researchers wear blindfolds
Question 4. What is the purpose of double-blinding?
o to obscure the results
o to increase the sample size
o the remove bias
o to make a non-significant result significant
Question 5. In a phase 3 trial, which group receives standard therapy?
• the control group
• both groups
• the experimental group
• neither group
Question 6. So if we INHBIT a COX-2 enzyme we should expect...
• less pain
• more pain
Question 7 So if we INHIBIT a COX-1 enzyme we should expect...
• GI protection (e.g. from acids)
• GI damage and bleeding
Question 8. Which produces the drug's intended effect?
• COX-2 inhibition
• COX-1 inhibition
Question 9. Which produces side effects?
• COX-1 inhibition
• COX-2 inhibition