What is a granuloma and what is its significance


Discussion Post

A 30-year-old male presents with acute trauma. The final diagnosis is DIC.

• Discuss the clotting mechanism.
• What do prolonged PT and aPTT tests indicate?
• Fibrin degradation and split products are common to DIC patients. Why?
• Identify two additional conditions that can initiate DIC and how?

A 19-year-old presents with a deep laceration on the left leg. After sutures are placed the patient is discharged.

• Discuss the pathophysiology of wound healing.
• What is a granuloma and what is its significance?
• Discuss graft versus host disease, would this be a concern for the patient? Discuss your answer.


A 60-year-old Type I diabetic presents with discoloration of his right leg. The pathogen is clostridium perfringens.

• Compare and contrast gas gangrene and wet gangrene.
• Compare and contrast apoptosis and necrosis.
• Identify the mechanism of cellular injury.
• How did diabetes contribute to this condition?

A 35-year-old female presents to the clinic with bulging eyes, hand tremors and unexplained weight loss. The final diagnosis is Grave's Disease.

• Compare and contrast Grave's Disease and Hashimoto's Disease.
• Would you expect this patient's TSH, T3 and T4 to be high or low? Explain your reasoning.
• Discuss the significance of Hürthle cells in thyroid disease.

The response must include a reference list. One-inch margins, double-space, Using Times New Roman 12 pnt font and APA style of writing and citations.

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