Assignment:
Define Pathogen
Define Infectious disease
Define Infection
Define Primary Infection
Define Secondary Infection
Define Opportunistic Infection
Define Accidental Infection
Define Pathogenicity
Define Virulence
Define Virulence Factors
Define Lethal dose
Outline the 4 steps a pathogen must complete to cause an infectious disease
What is the difference between direct and indirect transmission? Provide examples
What is a common vehicle transmission? Provide examples
What is the criteria for Airborne transmission? Provide examples
What are 3 criteria about skin that makes it an effective barrier against microbes?
What are 3 criteria about mucous membranes that makes it an effective barrier against microbes?
List one example of how a pathogen might penetrate a skin or mucous membrane barrier
Define Exotoxin and list at least 4 features they have
Define Endotoxin and list at least 4 features they have
List an example of a waterborne transmission disease
List an example of a airborne transmission disease
List an example of a contact transmission disease
List an example of a vector transmission disease
Influenza virus has an envelope that contains 2 types of protein spikes. Name and describe them
Why are spike antigens good at evolving?
Name 3 characteristics about latent and slow (persistent) Viral Infections
How are viruses able to bring about cancer cell division?
Describe the difference between Viruses and Retroviruses in regards to cancer development
What is a vaccination?
Define Attenuated Vaccines
Define Inactivated Vaccines
Define Subunit Vaccines
Define DNA Vaccines
Define Cutaneous Mycoses and its effect in humans
THE CONTROL OF MICROORGANISMS
Define Sterilization
Define Bactericidal
Define Bacteriostatic
Describe sterilization by heat
Describe sterilization by irradiation
Describe sterilization by filtration
What is disinfection?
List and describe 3 types of disinfectants
Describe the Kinetics of Cell death
Draw and describe the kinetics of cell death for any microorganisms.
ANTIMICROBIAL AGENTS
Define Antibiotic
What is a key component of antibiotics?
Define Infection
Name 5 antibiotics and the diseases they are typically used for
Name and describe 6 properties that antibiotics should have
What are 4 ways that antibiotics work?
Describe and give an example of disruption of cell membranes as it relates to antibiotics
Describe and give an example of inhibition of protein synthesis as it relates to antibiotics
Describe and give an example of inhibition of nucleic acid synthesis as it relates to antibiotics
Summarize in 5 sentences resistance to antibiotics
Provide 5 examples and describe 5 different ways bacteria can be resistant to antibiotics
Summarize in 5 sentences how bacteria resistance arises
Describe the pros and cons between broad-spectrum and narrow-spectrum antibiotics in 3 sentences
Define an Antiviral
Why are antiviral drugs not as common as antibacterial drugs?
List and provide a example of the 4 ways antivirals work
Describe how Antifungals work
List and describe 5 examples of Antifungal agents
Why is it hard to target Antiprotozoal Agents?
List and describe examples of Antiprotozoal Agents (At least 3)
Give a 3 sentence summary on the future of Antimicrobials (in your own words)