Problem: A clinically meaningful endpoint is: Need Assignment Help? Group of answer choices A. An endpoint that represents the clinical outcome of interest B. A laboratory measure or a physical sign that is used in therapeutic trials as a substitute for a clinically meaningful endpoint that is a direct measure of how a patient feels, functions, or survives and that is expected to predict the effect of the therapy. C. A characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention.