Question: As previously mentioned, G-quadruplexes are thought to play a role in the recruitment of transcription factors; however, these structures remain poorly understood. Recent studies have described a potential mechanism of global modulation of gene transcription in cancers involving G-quadruplexes. What are the implications of the c-Kit gene's G-rich sequences and G-quadruplexes in the regulation of its transcription, and how could this knowledge be leveraged for potential therapeutic interventions?