Assignment Task:
Chief Complaint: 26-year-old woman with two year history of mono-like illness.
In the past two years, Jamie' health has deteriorated, starting with a mono-like illness which resulted in fatigue, a sore throat, and swollen lymph nodes in the neck and groin. This was followed a few weeks later by a diarrheal illness marked by a 19-pound weight loss. Six months ago, Jamie developed a severe parasitic pneumonia which subsided only after intensive antibiotic treatment. Three months ago, she noted the appearance of silver-dollar-sized purple blotches on her skin that have still not gone away. In the past week, Jamie has progressively weakened, suffering from chills, weakness, and a high fever that has left her bedridden. Laboratory studies reveal a white blood cell count of 2.8 (2,800 WBCs per mm3; normal range is 4,500 to 11,000 WBCs per mm3) with a markedly reduced number of T-helper cells.
Jamie's pregnancy test comes back positive. What advice should she be given regarding her pregnancy and risk to the baby? Select all that apply.
1. Treatment with antiretroviral therapy is not recommended for infants who have acquired HIV.
2. The baby will be immune to HIV due to protection from IgG that crosses the placenta's due to protection from maternal IgG
3. She should not breastfeed the baby.
4. Antiretroviral therapy will help decrease her viral load and reduce her risk of transmitting HIV to the baby.
5. Neurologic involvement is common in newborns infected with HIV.