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Underlying physiological mechanism of malignant hyperthermia


Question: What is the underlying physiological mechanism of malignant hyperthermia, and why does it lead to a rapid rise in body temperature and severe muscle rigidity during surgery? What is the medical term for rigidity of the masseter muscle? How does a genetic mutation in the ryanodine receptor (RYR1) contribute to uncontrolled calcium release in skeletal muscle, and how does this explain the signs and symptoms seen in MH? During a malignant hyperthermia crisis, what are the specific responsibilities of the surgical technologist in assisting the surgical team? Why is it important for surgical technologists to be familiar with the MH emergency protocol, and how can regular simulation training improve their preparedness and response in a real event? Need Assignment Help?

 

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Other Subject: Underlying physiological mechanism of malignant hyperthermia
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