The outer membrane of Gram-negative bacteria contains lipopolysaccharide (LPS). When the Gram-negative bacterium dies, it releases LPS, which activates an immune reaction. The immune reaction can cause symptoms ranging from fever to shock to death. Because of the severe immune reaction elicited by free LPS, it is called an endotoxin. The effects caused by endotoxin are known as which of the following?
A. Infection cycle
B. Koch's postulate
c. immunopathogenesis