Sexually Transmitted Disease
Suppose a clinical trial is conducted to test the efficacy of a new drug, spectinomycin, for treating gonorrhea in females. Forty-six patients are given a 4-g daily does of the drug and are seen one week later, at which time 6 of the patients still have gonorrhea.
1) What is the best point estimate for p, the probability of a failure with the drug?
2) What is a 95 percent CI for p?
3) Suppose we know penicillin G at a daily dose of 4.8 megaunits has 10 percent failure rate. What can be said in comparing the two drugs?