Assignment:
Two circular DNA duplexes are catenated, or captured as interlocking rings. Draw a general mechanism that shows how these could be resolved into two free circles. You don't need to draw individual base pairs or a precise chemical mechanism of esterification by an active site tyrosine, but you do need to demonstrate generally how an enzyme could resolve these two tangled DNA strands (in this case, circles). Drawing the two duplexes in different colors or line widths will help a lot here. Must this be a type I or type II topoisomerase, and why? Must ATP have been used, and why?
Your answer must be in 1 page, typed, double-spaced, Times New Roman font (size 12), one-inch margins on all sides, APA format.