Please apply quantitative methods for the following case.
A pharmaceutical company conducted a study to evaluate the effect of an allergy relief medicine. 250 patients with symptoms that included itchy eyes and a skin rash received the new drug.
The results of the study are as follows:
80 of the patients treated experienced eye relief,
154 had their skin rash clear up, and
45 experiences relief of both itchy eyes and skin rash.
What is the probability that a patient who takes the drug will experience relief of at least one of the two symptoms?