q describe anthracycline cardiomyopathyit is due, Biology

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q describe anthracycline cardiomyopathyit is due

Q. Describe Anthracycline Cardiomyopathy?

It is due to anticancer agent doxorubion (Adriamycine), when the cumulative dose exceeds 450 mg/m² in subjects with normal hearts. In presence of heart disease or other risk factors viz. prior mediastinal radiation or when radiation treatment follows chemotherapy, the cardiomyopathy can occur at lower dosage.

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