Question: Robert Weinberg published a seminal paper that used a xenograft model with altered human cells to determine the minimal number of pathways need to be altered to obtain human cell tumorigenesis. What they observed was the following. Need Assignment Help?
Question options: They needed to introduce activated Ras G12V and a mutant p53 gene p53 and hTERT to have tumors form in nude mice. They needed to introduce a mutant p53 gene and introduce hTERT to have tumors form in nude mice. They needed to introduce activated Ras G12V and a mutant p53 gene to have tumors form in nude mice. They needed to introduce activated Ras G12V and hTERT and the SV40 virus Large-T to have tumors form in nude mice.