Problem: How would you differentiate between a case of hypoxemic respiratory failure that requires non-invasive support (like CPAP or BiPAP) and one that requires mechanical ventilation? What clinical signs would guide your decision? • For a patient with refractory hypoxemia (poor response to oxygen therapy), what advanced interventions might you consider and why? • When would it be appropriate to initiate ventilatory support in a patient with elevated PaCO2? How do you balance the need for support with the risk of further ventilatory failure? Need Assignment Help?