Is there a significant difference in the proportions of


A clinical trial is conducted comparing a new pain reliever for arthritis to a placebo. Participants are randomly assigned to receive the new medication or the placebo. The outcome is pain relief within 30 minutes. The data are shown in the following table:

 

Pain Relief

No Pain Relief

New Medication

44

76

Placebo

21

99

  1. Generate a 95% confidence interval for the proportion of patients on the new medication who report pain relief.

  2. Generate a 95% confidence interval for the difference in proportions of patients who report pain relief.

  3.  Is there a significant difference in the proportions of patients reporting pain relief? Run the test at 5% level of significance.

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