If barnase is a two-state protein that is denatured in


If Barnase is a two-state protein that is denatured in guanidium hydrochloride (GdnHCl). Barnase is 50% unfolded in 3 M GdnHCl, but 99% folded in 0.03 M GdnHCl. If 3 M solution of Barnase is diluted by a factor of 100 (that is to 0.03 M) it is observed to reach its new equilibrium in 12 minutes. Explain what is the folding rate constant of this protein.

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Chemistry: If barnase is a two-state protein that is denatured in
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