Discussion:
Determining Genotypes
A pregnant woman is worried about the chances of her child having hemophilia as both she and her husband have paternal grandfathers with hemophilia. Neither their parents nor their maternal grandparents have hemophilia.
1. What is the genotype of the paternal grandfathers who have hemophilia?
2. What is the genotype of their grandmothers and grandfathers without hemophilia?
3. Which of the pregnant couple's parents could carry the gene for hemophilia?
4. Does (or can) either of the pregnant couple carry the gene for hemophilia?
5. What are the possible genotypes of the couple?
6. Which is the likelihood that their child will have hemophilia?
7. How would things change for the couple's genotypes if their maternal grandfathers had hemophilia and their paternal ones didn't?