Case Scenario: Patient Medical History (attached)
Georgia is a 32 year old woman who has been suffering from recurrent (sometimes severe) headaches, and periods of fatigue since late childhood (~10-11 years of age). In her early twenties (21 years of age) she was diagnosed with gastroesophageal reflux disease (GERD) and began to experience periods of unexplained abdominal pain
Problem 1: How might an immune response contribute to abdominal pain?
Problem 2: What common immune response involves all of the markers elevated in Georgia's tests: tryptase, histamine and prostaglandin D2?
Problem 3: What do granulocytes all have in common both in structure and in immune response roles?
Problem 4: Describe the link between aberrant (too strong) mast cell responses and chronic multi-system inflammation.
Problem 5: Dermatographism - One of Georgia's symptoms was dermatographism. Using what you know of the immune response and knowing Georgia's diagnosis (MCAS) describe how her skin "writing" is occurring.
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Attachment:- Patient Medical History.rar