Consider three loci linked in the following order: A-B-C, where the A-B recombination frequency is 0.1 and the B-C recombination frequency 0.05.
(a) Assuming no interference, how many expected double crossovers are seen in a sample of 1000 gametes?
(b) Assumed 99% interference, how many are expected in a sample of 1000 gametes?
(c) Assuming 99% interference, how many gametes must be sampled to have a 95% probability that we see at least one double crossover?