How many cells can be produced in 500l bioreactor


Problem

A microcarrier culture will be used for cell therapy applications. This process uses non-porous microcarriers in a 500L bioreactor. After the cells are expanded on the microcarriers, they use release from the microcarriers using trypsin. The following properties are provided for the microcarriers:

Diameter= 160 um
Particle Density= 1.08 g/L
Specific area= 12000 cm2/gram
Max Capacity= 6000 Cells/cm2

If the culture uses 5 g/L of these microcarriers, how many cells can be produced in 500L bioreactor?

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Biology: How many cells can be produced in 500l bioreactor
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