How Lysosomal enzymes involved in the scavenging of aged
Lysosomal enzymes are also involved in the scavenging of aged and damaged cells. In several diseased states and also by intoxication with toxic chemicals, the lysosomal membranes are damaged, which leads to leakage of lysosomal enzymes. This results in certain clinical disorders. In certain genetic disorders, such as, glycogen storage disorders and Hurler's disease, the lysosomal enzymes, associated with the breakdown of glycogen and mucopolysaccharides, are missing or deficient. This leads to intracellular accumulation of these polysaccharides, leading to severe consequences. In many instances, disorders associated with lysosomal enzyme deficiencies often lead to severe mental disorders.