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How does a normal cell become a cancerous

How does a normal cell become a cancerous cell?
What is the role of telomerase? Explain the connection between telomerase activity and cancer.
How does the BCR-ABL mutation arise? Describe the relationship between the BCR-ABL mutation and chronic myeloid leukemia.
Imagine a scenario where both the telomerase and BCR-ABL proteins are active in the same cell. Describe what would happen to this cell.

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