How do sertoli cells direct the maturation of sperm, Biology

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How do sertoli cells direct the maturation of sperm

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Please answer of both the questions:

Question: How do Sertoli cells direct the maturation of sperm and why have they become an effective target for contraception?

Question: What is the difference between the transcriptional unit and the 3 primary regions within a mRNA transcript?

Please describe the the answer of the question.

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Biology: How do sertoli cells direct the maturation of sperm

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