Question: The disease Sickle-Cell Anemia is caused by ____. Need Assignment Help? Group of answer choices an accumulation of many DNA mutations in the hemoglobin protein found in red blood cells a single DNA mutation that alters the hemoglobin protein found in red blood cells bacteria carried by ticks that are transmitted to the blood of the host while the ticks are getting their blood meal a parasite carried by mosquitoes that infect red blood cells